Template-guided DNA recombination
نویسندگان
چکیده
منابع مشابه
Replication and Recombination Factors Contributing to Recombination-Dependent Bypass of DNA Lesions by Template Switch
Damage tolerance mechanisms mediating damage-bypass and gap-filling are crucial for genome integrity. A major damage tolerance pathway involves recombination and is referred to as template switch. Template switch intermediates were visualized by 2D gel electrophoresis in the proximity of replication forks as X-shaped structures involving sister chromatid junctions. The homologous recombination ...
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RNA non-enzymatic recombination reactions are of great interest within the hypothesis of the "RNA world", which argues that at some stage of prebiotic life development proteins were not yet engaged in biochemical reactions and RNA carried out both the information storage task and the full range of catalytic roles necessary in primitive self-replicating systems. Here we report on the study of re...
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Template polyhedra generalize intervals and octagons to polyhedra whose facets are orthogonal to a given set of arbitrary directions. They have been employed in the abstract interpretation of programs and, with particular success, in the reachability analysis of hybrid automata. While previously, the choice of directions has been left to the user or a heuristic, we present a method for the auto...
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OBJECTIVE The reconstruction of a defect involving complex cartilaginous structures such as the ear and nose is a difficult problem. Cartilage donor sites are limited, and the shaping of an ear or nose is dependent upon the surgeon's skills and experience. In this report, we propose to use resorbable plates that can be shaped to serve as a template for cartilage healing. METHODS A shell compo...
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Self-association of a decanucleotide d(TGGCCAAGCTp) in an aqueous solution is shown by UV spectroscopy, CD and sedimentation analysis to yield a pseudopolymeric (concatemeric) duplex having a geometry similar to that of DNA B-type. It is demonstrated that in conditions when the concatemeric duplex is stable a water-soluble carbodiimide induces efficient polymerization of the 3'- or 5'-phosphory...
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ژورنال
عنوان ژورنال: Theoretical Computer Science
سال: 2005
ISSN: 0304-3975
DOI: 10.1016/j.tcs.2004.06.028